The Biology of Slowing & Reversing Aging – Dr. David Sinclair & Dr. Andrew Huberman

2 legends, free education. I understood at least 45% of it lol. The key takeaway in this video comes all the way at the end: 01:59:00 Public Science Education, Personal Health

It’s when Andrew Huberman thanks David Sinclair for bringing real scientific and medical knowledge to the public for free. He called Sinclair the innovator in this arena and hopes more professionals join in. Sinclair said of the current state of sharing knowledge via the Internet “This has never been able to be possible until this time right now”

As a digital professional, I’m able to work and learn at the same time and discussions like these have become an invaluable resource. I hope you also gain new insight as a result!

Timestamps:
00:00:00 Dr. David Sinclair, Harvard Medical School
00:03:30 ROKA, InsideTracker, Magic Spoon
00:07:45 “Aging as a Disease” vs. Longevity & Anti-Aging
00:10:23 What Causes Aging? The Epigenome
00:15:53 Cosmetic Aging
00:17:15 Development Never Stops, Horvath Clock
00:20:12 Puberty Rate as a Determinant of Aging Rate
00:23:00 Fasting, Hunger & Food Choices
00:32:44 Fasting Schedules, Long Fasts, (Macro)Autophagy
00:34:50 Caffeine, Electrolytes
00:35:56 Blood Glucose & the Sirtuins; mTOR
00:37:55 Amino Acids: Leucine, “Pulsing”
00:44:35 Metformin, Berberine
00:50:29 Resveratrol, Wine
00:53:20 What Breaks a Fast?
00:56:45 Resveratrol, NAD, NMN, NR; Dosage, Timing
01:09:10 Are Artificial Sweeteners Bad for Us?
01:12:04 Iron Load & Aging
01:15:05 Blood Work Analysis
01:19:37 C-Reactive Protein, Cholesterol: Serum & Dietary
01:26:02 Amino Acids, Plants, Antioxidants
01:33:45 Behaviors That Extend Lifespan, Testosterone, Estrogen
01:40:35 Neuroplasticity & Neural Repair
01:46:19 Ice Baths, Cold Showers, “Metabolic Winter”
01:48:07 Obesity & How It Accelerates Aging, GnRH
01:52:10 Methylation, Methylene Blue, Cigarettes
01:56:17 X-Rays
01:59:00 Public Science Education, Personal Health
02:05:40 The Sinclair Test You Can Take: www.doctorsinclair.com
02:08:13 Zero-Cost Support & Resources, Sponsors, Patreon, Supplements, Instagram

I'm a hands-on health coach, strength trainer, yoga teacher and 25 year work from home digital professional in Orange, CT and I live the lifestyle I talk about.

Certified Yoga Teacher

Certified Health Coach

25 Year WFH Professional

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Surviving Family Vacation, Alcohol while Continuing to Train

Well I did it. 7 days on Hilton Head Island South Carolina at the Omni with no loss of progress. I fully detached my digital brain and focused on relaxing. It's really a very relaxing resort even with an energetic 6 year old. We got really perfect weather for pool, beach and a couple great runs. I did a 7 miler early on and a 9 miler around half way through. I was also able to do a ton of walking, swimming and everything that comes with a 6 year old at a pool. Games, throwing balls, throwing him, marco polo you name it. He keeps my old ass moving!

However, I also indulged on many beers along with a few margaritas. I averaged 3-6 beers per day. So to offset this indulgence I simply ate ZERO typical vacation nonsense like fries, baked goods, fried food, desert etc. I brought much of my own food, high quality portable protein and only got their fruit and one day had the breakfast buffet where I only had eggs, bacon, coffee and water.

I am super thankful to be able to shut alcohol off and turn alcohol on at will. There's something magical to me about days of sun, some deliberate exercise, tons of natural movement and good beer. I literally never sleep better.

I won't have another drink for weeks.

I got a bit of bloat but didn't gain weight, in fact I lost a bit - just feeling flabby and bloated even though it's mostly in my head I can notice less muscle definition and belly fat after just 1 week of consistent beer.

My recommendation for anyone, whether training for a marathon or just not wanting to get your progress destroyed on vacation is to fully avoid nonsense food and make sure to have the forethought to bring your own.

I also (like a madman) brought my IronMaster dumbbells and did 2 floor strength sessions along with one day where I incorporated around 500 air squats.

Upon return, after a 16 hour car trip (UGH!) I did a Bikram style yoga class in 110 degrees and today I hit the woods for a short hike, few hill sprints, 560 air squats and a new PR of 460 in ONE SET.

I have my home food going and doing a bit of a "detox" (I hate that word) of simply eating clean, single ingredient protein 170-200g per day, fruit and nothing else. I'll add some of my clean granola ahead of my next training run which I expect to be Fri or Sat.

NYC Marathon Training: Surviving Family Vacation - Kids, Food, Alcohol #NYCMarathon #hiltonhead

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